You will lose a portion of your Life Gauge if you take damage from enemy attacks, or if you make contact with enemies or harmful objects. If you have Medicine in your possession when your Life Gauge becomes completely depleted, your Life will be automatically restored. However, the amount restored is random. When your Life Gauge is low, find a Hospital to fully recover your Life Gauge. If you find an Extra Heart inside a treasure chest, your Life Gauge will be increased by one Heart.

Note: You can only hold a maximum of three Medicines.